approach to mental retardation and global developmental delay

Diagnostic evaluation of developmental delay/mental retardation: An overview.

Mental retardation (MR) is one of the few clinically important disorders for which the etiopathogenesis is still poorly understood. It is a condition of great concern for public health and society. MR is currently defined as a significant impairment of cognitive and adaptive functions, with onset before age 18 years. It may become evident during infancy or early childhood as developmental delay...

Aetiologic spectrum of mental retardation & developmental delay in India

BACKGROUND & OBJECTIVES The aetiology of mental retardation is varied and difficult to establish. Reports from India on the spectrum of underlying causative conditions are lacking. This retrospective study was conducted to establish the various aetiologies of mental retardation (MR) and developmental delay (DD) in patients attending a medical genetics centre in north India and to assess the con...

Early Experience and Early Intervention for Children ‘‘at Risk’’for Developmental Delay and Mental Retardation

THE ORIGINS OF EARLY INTERVENTION RESEARCH FOR ‘‘AT RISK’’ INFANTS AND CHILDREN In 1801, a French surgeon, Itard, began an educational intervention with an 11 year old boy that has since become classic [Itard, 1932]. From his work with the child he found running naked and wild in a forest (‘‘the savage of Aveyron’’) emerged hope, as well as understanding, about the role of early experience and ...

Three Supernumerary Marker Chromosomes in a Patient with Developmental Delay, Mental Retardation, and Dysmorphic Features

We characterized three supernumerary marker chromosomes (SMCs) simultaneously present in a 2-year- and 10-month-old male patient with mental retardation and dysmorphic features. Peripheral blood chromosome analysis revealed two to three SMCs in 25/26 cells analyzed. The remaining one cell had one SMC. Microarray comparative genomic hybridization (aCGH) showed mosaicism for gains of 5q35.3, 15q1...

Clinical profile of young children with mental retardation and developmental delay in Hong Kong.

OBJECTIVE To report the clinical profile of children with mental retardation and developmental delay diagnosed by the Child Assessment Service. DESIGN Retrospective study. SETTING Child Assessment Service, Department of Health, Hong Kong. PARTICIPANTS Data pertaining to the children with mental retardation and developmental delay were drawn from an in-house clinical information system in ...

A community mental health approach to mental retardation.